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IL-2/IL-15 activate the human clonally-restricted KIR3DL1 reverse promoter
Killer cell immunoglobulin-like receptors (KIR) are expressed in a clonally-restricted fashion by human natural killer (NK) cells and allow detection of aberrant cells with low MHC class I levels. Clonally-restricted KIR transcription is maintained by demethylation of the proximal promoter. Antisens...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742563/ https://www.ncbi.nlm.nih.gov/pubmed/23328843 http://dx.doi.org/10.1038/gene.2012.62 |