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The DnaA Cycle in Escherichia coli: Activation, Function and Inactivation of the Initiator Protein

This review summarizes the mechanisms of the initiator protein DnaA in replication initiation and its regulation in Escherichia coli. The chromosomal origin (oriC) DNA is unwound by the replication initiation complex to allow loading of DnaB helicases and replisome formation. The initiation complex...

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Detalles Bibliográficos
Autores principales: Katayama, Tsutomu, Kasho, Kazutoshi, Kawakami, Hironori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742627/
https://www.ncbi.nlm.nih.gov/pubmed/29312202
http://dx.doi.org/10.3389/fmicb.2017.02496