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The DnaA Cycle in Escherichia coli: Activation, Function and Inactivation of the Initiator Protein
This review summarizes the mechanisms of the initiator protein DnaA in replication initiation and its regulation in Escherichia coli. The chromosomal origin (oriC) DNA is unwound by the replication initiation complex to allow loading of DnaB helicases and replisome formation. The initiation complex...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742627/ https://www.ncbi.nlm.nih.gov/pubmed/29312202 http://dx.doi.org/10.3389/fmicb.2017.02496 |