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The classic signalling and trans‐signalling of interleukin‐6 are both injurious in podocyte under high glucose exposure

Interleukin‐6 (IL‐6) is a multifunctional cytokine that employs IL‐6 classic and trans‐signalling pathways, and these two signal channels execute different or even opposite effects in certain diseases. As a cardinal event of diabetic kidney disease (DKD), whether the podocyte abnormalities are assoc...

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Detalles Bibliográficos
Autores principales: Lei, Chun‐Tao, Su, Hua, Ye, Chen, Tang, Hui, Gao, Pan, Wan, Cheng, He, Fang‐Fang, Wang, Yu‐Mei, Zhang, Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742688/
https://www.ncbi.nlm.nih.gov/pubmed/28881473
http://dx.doi.org/10.1111/jcmm.13314