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The classic signalling and trans‐signalling of interleukin‐6 are both injurious in podocyte under high glucose exposure
Interleukin‐6 (IL‐6) is a multifunctional cytokine that employs IL‐6 classic and trans‐signalling pathways, and these two signal channels execute different or even opposite effects in certain diseases. As a cardinal event of diabetic kidney disease (DKD), whether the podocyte abnormalities are assoc...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742688/ https://www.ncbi.nlm.nih.gov/pubmed/28881473 http://dx.doi.org/10.1111/jcmm.13314 |