Mesenchymal stem cells deliver exogenous miR‐21 via exosomes to inhibit nucleus pulposus cell apoptosis and reduce intervertebral disc degeneration

Although mesenchymal stem cells (MSCs) transplantation into the IVD (intervertebral disc) may be beneficial in inhibiting apoptosis of nucleus pulposus cells (NPCs) and alleviating IVD degeneration, the underlying mechanism of this therapeutic process has not been fully explained. The purpose of thi...

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Detalles Bibliográficos
Autores principales: Cheng, Xiaofei, Zhang, Guoying, Zhang, Liang, Hu, Ying, Zhang, Kai, Sun, Xiaojiang, Zhao, Changqing, Li, Hua, Li, Yan Michael, Zhao, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742691/
https://www.ncbi.nlm.nih.gov/pubmed/28805297
http://dx.doi.org/10.1111/jcmm.13316

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742691/
https://www.ncbi.nlm.nih.gov/pubmed/28805297
http://dx.doi.org/10.1111/jcmm.13316

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