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Stabilization of hypoxia inducible factor by cobalt chloride can alter renal epithelial transport

Given the importance of the transcriptional regulator hypoxia‐inducible factor‐1 (HIF‐1) for adaptive hypoxia responses, we examined the effect of stabilized HIF‐1α on renal epithelial permeability and directed sodium transport. This study was motivated by histological analysis of cystic kidneys sho...

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Detalles Bibliográficos
Autores principales: Nag, Subhra, Resnick, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742700/
https://www.ncbi.nlm.nih.gov/pubmed/29263117
http://dx.doi.org/10.14814/phy2.13531