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In vitro cellular models of human hepatic fatty acid metabolism: differences between Huh7 and HepG2 cell lines in human and fetal bovine culturing serum

Human primary hepatocytes are the gold standard for investigating lipid metabolism in nonalcoholic fatty liver disease (NAFLD); however, due to limitations including availability and donor variability, the hepatoma cell lines Huh7 and HepG2 are commonly used. Culturing these cell lines in human seru...

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Detalles Bibliográficos
Autores principales: Gunn, Pippa J., Green, Charlotte J., Pramfalk, Camilla, Hodson, Leanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742701/
https://www.ncbi.nlm.nih.gov/pubmed/29263118
http://dx.doi.org/10.14814/phy2.13532