Macrophage migration inhibitory factor mediates protease‐activated receptor 4‐induced bladder pain through urothelial high mobility group box 1

Macrophage migration inhibitory factor (MIF) mediates pain although the mechanisms are not well understood. Urothelial activation of protease activated receptor 4 (PAR4) results in urothelial MIF release, urothelial high mobility group box 1 (HMGB1) release and bladder pain in mice without bladder i...

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Detalles Bibliográficos
Autores principales: Ma, Fei, Kouzoukas, Dimitrios E., Meyer‐Siegler, Katherine L., Hunt, David E., Leng, Lin, Bucala, Richard, Vera, Pedro L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742707/
https://www.ncbi.nlm.nih.gov/pubmed/29263120
http://dx.doi.org/10.14814/phy2.13549

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742707/
https://www.ncbi.nlm.nih.gov/pubmed/29263120
http://dx.doi.org/10.14814/phy2.13549

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