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Potential role of the methylation of VEGF gene promoter in response to hypoxia in oxygen‐induced retinopathy: beneficial effect of the absence of AQP4

Hypoxia‐dependent accumulation of vascular endothelial growth factor (VEGF) plays a major role in retinal diseases characterized by neovessel formation. In this study, we investigated whether the glial water channel Aquaporin‐4 (AQP4) is involved in the hypoxia‐dependent VEGF upregulation in the ret...

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Detalles Bibliográficos
Autores principales: Pisani, Francesco, Cammalleri, Maurizio, Dal Monte, Massimo, Locri, Filippo, Mola, Maria Grazia, Nicchia, Grazia Paola, Frigeri, Antonio, Bagnoli, Paola, Svelto, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742711/
https://www.ncbi.nlm.nih.gov/pubmed/28940930
http://dx.doi.org/10.1111/jcmm.13348