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Disulfiram combined with copper inhibits metastasis and epithelial–mesenchymal transition in hepatocellular carcinoma through the NF‐κB and TGF‐β pathways

Late‐stage hepatocellular carcinoma (HCC) usually has a low survival rate because of the high risk of metastases and the lack of an effective cure. Disulfiram (DSF) has copper (Cu)‐dependent anticancer properties in vitro and in vivo. The present work aims to explore the anti‐metastasis effects and...

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Detalles Bibliográficos
Autores principales: Li, Yi, Wang, Li‐Hui, Zhang, Hao‐Tian, Wang, Ya‐Ting, Liu, Shuai, Zhou, Wen‐Long, Yuan, Xiang‐Zhong, Li, Tian‐Yang, Wu, Chun‐Fu, Yang, Jing‐Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742719/
https://www.ncbi.nlm.nih.gov/pubmed/29148232
http://dx.doi.org/10.1111/jcmm.13334