The enhancement of combination of berberine and metformin in inhibition of DNMT1 gene expression through interplay of SP1 and PDPK1

Berberine (BBR), one of active alkaloid found in the rhizome, exhibited anti‐cancer properties. We have showed that BBR inhibited growth of non‐small cell lung cancer (NSCLC) cells through mitogen‐activated protein kinase (MAPK)‐mediated increase in forkhead box O3a (FOXO3a). However, the in‐depth m...

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Detalles Bibliográficos
Autores principales: Zheng, Fang, Wu, JingJing, Tang, Qing, Xiao, Qian, Wu, WanYin, Hann, Swei Sunny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742731/
https://www.ncbi.nlm.nih.gov/pubmed/28840963
http://dx.doi.org/10.1111/jcmm.13347

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742731/
https://www.ncbi.nlm.nih.gov/pubmed/28840963
http://dx.doi.org/10.1111/jcmm.13347

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