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Silencing of CA1 mRNA in tumour cells does not change the gene expression of the extracellular matrix proteins

We report the silencing of CA1 mRNA in PC3 and MDA cells. The levels of mRNA coding CA1 protein in the knock‐down mRNA (CA1 siRNA) cells have been measured by RT‐PCR and were approximately 5% (PC3) and 20% (MDA‐MB‐231), respectively, of the level of control (Mock siRNA) used during silencing. In PC3...

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Detalles Bibliográficos
Autores principales: Vulic, Radivojka, Tyciakova, Silvia, Dubrovcakova, Maria, Skultety, Ludovit, Lakota, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742735/
https://www.ncbi.nlm.nih.gov/pubmed/28782909
http://dx.doi.org/10.1111/jcmm.13315