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Non-Canonical Thinking for Targeting ALK-Fusion Onco-Proteins in Lung Cancer
Anaplastic lymphoma kinase (ALK) gene rearrangements have been identified in lung cancer at 3–7% frequency, thus representing an important subset of genetic lesions that drive oncogenesis in this disease. Despite the availability of multiple FDA-approved small molecule inhibitors targeting ALK fusio...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742812/ https://www.ncbi.nlm.nih.gov/pubmed/29189709 http://dx.doi.org/10.3390/cancers9120164 |