Double-stranded phosphodiester cytosine-guanine oligodeoxynucleotide complexed with calcium phosphate as a potent vaccine adjuvant for activating cellular and Th1-type humoral immunities

Conventional class B cytosine-guanine (CpG) (CpG-B) oligodeoxynucleotide (ODNs) consisting of a single-stranded (ss) phosphorothioate (PT) backbone (ss CpG-B-PT) is converted from a proinflammatory cytokine inducer to a type-I interferon (IFN) inducer when complexed with cationic materials. In this...

Descripción completa

Detalles Bibliográficos
Autores principales: Hanagata, Nobutaka, Li, Xianglan, Chen, Min-Hua, Li, Jie, Hattori, Shinya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5743182/
https://www.ncbi.nlm.nih.gov/pubmed/29317815
http://dx.doi.org/10.2147/IJN.S152141

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5743182/
https://www.ncbi.nlm.nih.gov/pubmed/29317815
http://dx.doi.org/10.2147/IJN.S152141

Ejemplares similares