Acid-degradable Dextran as an Image Guided siRNA Carrier for COX-2 Downregulation

Purpose: Effective in vivo delivery of siRNA to silence genes is a highly sought-after goal in the treatment of multiple diseases. Cyclooxygenase-2 (COX-2) is a major mediator of inflammation and its effective and specific downregulation has been of major interest to treat conditions ranging from au...

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Detalles Bibliográficos
Autores principales: Chen, Zhihang, Krishnamachary, Balaji, Penet, Marie-France, Bhujwalla, Zaver M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5743456/
https://www.ncbi.nlm.nih.gov/pubmed/29290789
http://dx.doi.org/10.7150/thno.21052

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5743456/
https://www.ncbi.nlm.nih.gov/pubmed/29290789
http://dx.doi.org/10.7150/thno.21052

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