A Mucin1 C-terminal Subunit-directed Monoclonal Antibody Targets Overexpressed Mucin1 in Breast Cancer

Background: Mucin1 (MUC1) is a highly glycosylated transmembrane protein that has gained attention because of its overexpression in various cancers. However, MUC1-targeted therapeutic antibodies have not yet been approved for cancer therapy. MUC1 is cleaved to two subunits, MUC1-N and MCU1-C. MUC1-N...

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Detalles Bibliográficos
Autores principales: Wu, Guang, Kim, Dongbum, Kim, Jung Nam, Park, Sangkyu, Maharjan, Sony, Koh, Heeju, Moon, Kyungduk, Lee, Younghee, Kwon, Hyung-Joo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5743461/
https://www.ncbi.nlm.nih.gov/pubmed/29290794
http://dx.doi.org/10.7150/thno.21278

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5743461/
https://www.ncbi.nlm.nih.gov/pubmed/29290794
http://dx.doi.org/10.7150/thno.21278

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