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Histidine-rich Modification of a Scorpion-derived Peptide Improves Bioavailability and Inhibitory Activity against HSV-1

Rationale: HSV is one of the most widespread human viral pathogens. HSV-1 infects a large portion of the human population and causes severe diseases. The current clinical treatment for HSV-1 is based on nucleoside analogues, the use of which is limited due to drug resistance, side effects and poor b...

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Detalles Bibliográficos
Autores principales: Zeng, Zhengyang, Zhang, Runhong, Hong, Wei, Cheng, Yuting, Wang, Huijuan, Lang, Yange, Ji, Zhenglin, Wu, Yingliang, Li, Wenxin, Xie, Youli, Cao, Zhijian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5743469/
https://www.ncbi.nlm.nih.gov/pubmed/29290802
http://dx.doi.org/10.7150/thno.21425