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Histidine-rich Modification of a Scorpion-derived Peptide Improves Bioavailability and Inhibitory Activity against HSV-1
Rationale: HSV is one of the most widespread human viral pathogens. HSV-1 infects a large portion of the human population and causes severe diseases. The current clinical treatment for HSV-1 is based on nucleoside analogues, the use of which is limited due to drug resistance, side effects and poor b...
Autores principales: | Zeng, Zhengyang, Zhang, Runhong, Hong, Wei, Cheng, Yuting, Wang, Huijuan, Lang, Yange, Ji, Zhenglin, Wu, Yingliang, Li, Wenxin, Xie, Youli, Cao, Zhijian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5743469/ https://www.ncbi.nlm.nih.gov/pubmed/29290802 http://dx.doi.org/10.7150/thno.21425 |
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