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An Albumin-binding Polypeptide Both Targets Cytotoxic T Lymphocyte Vaccines to Lymph Nodes and Boosts Vaccine Presentation by Dendritic Cells

Rationale: Albumin-binding carriers have been shown to target cytotoxic T lymphocyte (CTL) vaccines to lymph nodes (LNs) and improve the efficacy of the vaccines. However, it was not clear whether the improved efficacy is solely due to the LN targeting, which prompted this study. Methods: First, we...

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Detalles Bibliográficos
Autores principales: Wang, Peng, Zhao, Peng, Dong, Shuyun, Xu, Tiefeng, He, Xiao, Chen, Mingnan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5743471/
https://www.ncbi.nlm.nih.gov/pubmed/29290804
http://dx.doi.org/10.7150/thno.21691