Methylation-associated silencing of miR-193a-3p promotes ovarian cancer aggressiveness by targeting GRB7 and MAPK/ERK pathways

Human growth factor receptor-bound protein-7 (GRB7) is a pivotal mediator involved in receptor tyrosine kinase signaling and governing diverse cellular processes. Aberrant upregulation of GRB7 is frequently associated with the progression of human cancers. However, the molecular mechanisms leading t...

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Detalles Bibliográficos
Autores principales: Chen, Kangmei, Liu, Michelle Xin, Mak, Celia Sze-Ling, Yung, Mingo Ming-Ho, Leung, Thomas Ho-Yin, Xu, Dakang, Ngu, Siew-Fei, Chan, Karen Kar-Loen, Yang, Huijuan, Ngan, Hextan Yuen-Sheung, Chan, David Wai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5743558/
https://www.ncbi.nlm.nih.gov/pubmed/29290818
http://dx.doi.org/10.7150/thno.22377

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5743558/
https://www.ncbi.nlm.nih.gov/pubmed/29290818
http://dx.doi.org/10.7150/thno.22377

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