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circRNA Mediates Silica-Induced Macrophage Activation Via HECTD1/ZC3H12A-Dependent Ubiquitination

Rationale: Phagocytosis of silicon dioxide (SiO(2)) into lung cells causes an inflammatory cascade that results in fibroblast proliferation and migration, followed by fibrosis. Circular RNAs (circRNAs) are a subclass of non-coding RNAs detected within mammalian cells; however, researchers have not d...

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Detalles Bibliográficos
Autores principales: Zhou, Zewei, Jiang, Rong, Yang, Xiyue, Guo, Huifang, Fang, Shencun, Zhang, Yingming, Cheng, Yusi, Wang, Jing, Yao, Honghong, Chao, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5743568/
https://www.ncbi.nlm.nih.gov/pubmed/29290828
http://dx.doi.org/10.7150/thno.21648