Novel, Anti-hTNF-α Variable New Antigen Receptor Formats with Enhanced Neutralizing Potency and Multifunctionality, Generated for Therapeutic Development

The management of chronic inflammatory diseases, such as inflammatory bowel disease, psoriasis, and rheumatoid arthritis has significantly improved over the last decade with the clinical availability of anti-TNF-α biologics. Despite this undoubted treatment success, a combination of acquired resista...

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Detalles Bibliográficos
Autores principales: Ubah, Obinna C., Steven, John, Kovaleva, Marina, Ferguson, Laura, Barelle, Charlotte, Porter, Andrew J. R., Barelle, Caroline J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5743654/
https://www.ncbi.nlm.nih.gov/pubmed/29312310
http://dx.doi.org/10.3389/fimmu.2017.01780

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5743654/
https://www.ncbi.nlm.nih.gov/pubmed/29312310
http://dx.doi.org/10.3389/fimmu.2017.01780

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