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Nuclear EGFR and Integrator/Super Elongation Complex concurrently binds to Immediate Early Genes for gene transactivation
The gene transactivation function of nuclear EGFR (nEGFR) has been studied by investigating the genomic co-occupancies of nEGFR and RNA Polymerase II (RNAPII). However, due to RNAPII pausing, the co-recruitment of RNAPII and nEGFR does not necessarily represent productive transactivation. In this st...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Ivyspring International Publisher
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5743717/ https://www.ncbi.nlm.nih.gov/pubmed/29290775 http://dx.doi.org/10.7150/jca.21925 |