Cargando…

Nuclear EGFR and Integrator/Super Elongation Complex concurrently binds to Immediate Early Genes for gene transactivation

The gene transactivation function of nuclear EGFR (nEGFR) has been studied by investigating the genomic co-occupancies of nEGFR and RNA Polymerase II (RNAPII). However, due to RNAPII pausing, the co-recruitment of RNAPII and nEGFR does not necessarily represent productive transactivation. In this st...

Descripción completa

Detalles Bibliográficos
Autor principal:	Wong, Victor Chun-Lam
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5743717/ https://www.ncbi.nlm.nih.gov/pubmed/29290775 http://dx.doi.org/10.7150/jca.21925

Ejemplares similares

Roles of the Nuclear Lamina in Stable Nuclear Association and Assembly of a Herpesviral Transactivator Complex on Viral Immediate-Early Genes
por: Silva, Lindsey, et al.
Publicado: (2012)

Inhibition of the Super Elongation Complex Suppresses Herpes Simplex Virus Immediate Early Gene Expression, Lytic Infection, and Reactivation from Latency
por: Alfonso-Dunn, Roberto, et al.
Publicado: (2020)

Nuclear PKM2 regulates β-catenin transactivation upon EGFR activation
por: Yang, Weiwei, et al.
Publicado: (2011)

T-bet Activates Th1 Genes through Mediator and the Super Elongation Complex
por: Hertweck, Arnulf, et al.
Publicado: (2016)

EGFR transactivation contributes to neuroinflammation in Streptococcus suis meningitis
por: Yang, Xiao-Pei, et al.
Publicado: (2016)

EGFR transactivates RON to drive oncogenic crosstalk
por: Franco Nitta, Carolina, et al.
Publicado: (2021)

Building a super elongation complex for HIV
por: Hill, Christopher P, et al.
Publicado: (2013)

PARP1′s Involvement in RNA Polymerase II Elongation: Pausing and Releasing Regulation through the Integrator and Super Elongation Complex
por: Matveeva, Elena A., et al.
Publicado: (2022)

Rapamycin Induces Transactivation of the EGFR and Increases Cell Survival
por: Chaturvedi, Deepti, et al.
Publicado: (2009)

Characterizing the Interaction between the HTLV-1 Transactivator Tax-1 with Transcription Elongation Factor ELL2 and Its Impact on Viral Transactivation
por: Kohrt, Stephan, et al.
Publicado: (2021)

Acetylation reduces SOX9 nuclear entry and ACAN gene transactivation in human chondrocytes
por: Bar Oz, Michal, et al.
Publicado: (2016)

Brk/PTK6 Sustains Activated EGFR Signaling through Inhibiting EGFR Degradation and Transactivating EGFR
por: Li, X, et al.
Publicado: (2012)

Transactivation of EGFR by LPS Induces COX-2 Expression in Enterocytes
por: McElroy, Steven J., et al.
Publicado: (2012)

Transactivation by low and high levels of human p53 reveals new physical rules of engagement and novel super-transactivation sequences
por: Menendez, Daniel, et al.
Publicado: (2012)

Gene Transactivation and Transrepression in MYC-Driven Cancers
por: Scafuro, Marika, et al.
Publicado: (2021)

Hepatocellular carcinoma chemoprevention by targeting the angiotensin-converting enzyme and EGFR transactivation
por: Crouchet, Emilie, et al.
Publicado: (2022)

Concurrent hypermethylation of DNMT1, MGMT and EGFR genes in progression of gliomas
por: Gömöri, Éva, et al.
Publicado: (2012)

The super elongation complex drives transcriptional addiction in MYCN-amplified neuroblastoma
por: Wang, Donghai, et al.
Publicado: (2023)

Mechanisms of transactivation by nuclear factor of activated T cells-1
Publicado: (1996)

AFF4 binding to Tat-P-TEFb indirectly stimulates TAR recognition of super elongation complexes at the HIV promoter
por: Schulze-Gahmen, Ursula, et al.
Publicado: (2014)

Upregulating endogenous genes by an RNA-programmable artificial transactivator
por: Fimiani, Cristina, et al.
Publicado: (2015)

Aptamer‐Mediated Reversible Transactivation of Gene Expression by Light
por: Renzl, Christian, et al.
Publicado: (2020)

The C-Terminal Transactivation Domain of STAT1 Has a Gene-Specific Role in Transactivation and Cofactor Recruitment
por: Parrini, Matthias, et al.
Publicado: (2018)

Schizosaccharomyces pombe Pol II transcription elongation factor ELL functions as part of a rudimentary super elongation complex
por: Gopalan, Sneha, et al.
Publicado: (2018)

Identification and characterization of the binding sequences and target genes of p53 lacking the 1st transactivation domain
por: Suzuki, Shiori, et al.
Publicado: (2020)

Differential Nuclear Translocation and Transactivation Potential of β-Catenin and Plakoglobin
por: Simcha, Inbal, et al.
Publicado: (1998)

P-TEFb, the Super Elongation Complex and Mediator Regulate a Subset of Non-paused Genes during Early Drosophila Embryo Development
por: Dahlberg, Olle, et al.
Publicado: (2015)

Improved single-chain transactivators of the Tet-On gene expression system
por: Zhou, Xue, et al.
Publicado: (2007)

A procedure for Dex-induced gene transactivation in Arabidopsis ovules
por: Schubert, Jasmin, et al.
Publicado: (2022)

Room-temperature super-elongation in high-entropy alloy nanopillars
por: Zhang, Qian, et al.
Publicado: (2023)

The Expression and Roles of the Super Elongation Complex in Mouse Cochlear Lgr5+ Progenitor Cells
por: Chen, Yin, et al.
Publicado: (2021)

DNA-binding of the Tet-transactivator curtails antigen-induced lymphocyte activation in mice
por: Ottina, Eleonora, et al.
Publicado: (2017)

Sonic Hedgehog modulates EGFR dependent proliferation of neural stem cells during late mouse embryogenesis through EGFR transactivation
por: Reinchisi, Gisela, et al.
Publicado: (2013)

Nuclear Factor of Activated T Cells (NFAT)-dependent Transactivation Regulated by the Coactivators p300/CREB-binding Protein (CBP)
por: García-Rodríguez, Carmen, et al.
Publicado: (1998)

Control of Embryonic Stem Cell Identity by BRD4-Dependent Transcriptional Elongation of Super-Enhancer-Associated Pluripotency Genes
por: Micco, Raffaella Di, et al.
Publicado: (2014)

Correction: P-TEFb, the Super Elongation Complex and Mediator Regulate a Subset of Non-paused Genes during Early Drosophila Embryo Development
Publicado: (2015)

EGFR and K-ras gene mutation status in squamous cell anal carcinoma: a role for concurrent radiation and EGFR inhibitors?
por: Paliga, A, et al.
Publicado: (2012)

Concurrent gene alterations with EGFR mutation and treatment efficacy of EGFR-TKIs in Chinese patients with non-small cell lung cancer
por: Hu, Wentao, et al.
Publicado: (2017)

GPR54 (KISS1R) Transactivates EGFR to Promote Breast Cancer Cell Invasiveness
por: Zajac, Mateusz, et al.
Publicado: (2011)

Inhibition of Both HIV-1 Reverse Transcription and Gene Expression by a Cyclic Peptide that Binds the Tat-Transactivating Response Element (TAR) RNA
por: Lalonde, Matthew S., et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_q2nb4u9b4ub0imk07hnd1kiig8