KPNA2 promotes migration and invasion in epithelial ovarian cancer cells by inducing epithelial-mesenchymal transition via Akt/GSK-3β/Snail activation

Background: Increased karyopherin alpha 2 (KPNA2) expression has been demonstrated in epithelial ovarian carcinoma (EOC) tissue. However, its role in the disease is not clear. Here, we investigate the mechanism of involvement of KPNA2 in EOC. Methods: Stable cell lines expressing KPNA2, or KPNA2 shR...

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Detalles Bibliográficos
Autores principales: Huang, Long, Zhou, Yun, Cao, Xin-Ping, Lin, Jia-Xin, Zhang, Lan, Huang, Shu-Ting, Zheng, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5743723/
https://www.ncbi.nlm.nih.gov/pubmed/29290781
http://dx.doi.org/10.7150/jca.20879

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5743723/
https://www.ncbi.nlm.nih.gov/pubmed/29290781
http://dx.doi.org/10.7150/jca.20879

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