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Functionally Convergent B Cell Receptor Sequences in Transgenic Rats Expressing a Human B Cell Repertoire in Response to Tetanus Toxoid and Measles Antigens

The identification and tracking of antigen-specific immunoglobulin (Ig) sequences within total Ig repertoires is central to high-throughput sequencing (HTS) studies of infections or vaccinations. In this context, public Ig sequences shared by different individuals exposed to the same antigen could b...

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Detalles Bibliográficos
Autores principales: Bürckert, Jean-Philippe, Dubois, Axel R. S. X., Faison, William J., Farinelle, Sophie, Charpentier, Emilie, Sinner, Regina, Wienecke-Baldacchino, Anke, Muller, Claude P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5743747/
https://www.ncbi.nlm.nih.gov/pubmed/29312330
http://dx.doi.org/10.3389/fimmu.2017.01834