Neuronal ICAM-5 Inhibits Microglia Adhesion and Phagocytosis and Promotes an Anti-inflammatory Response in LPS Stimulated Microglia

The intercellular adhesion molecule-5 (ICAM-5) regulates neurite outgrowth and synaptic maturation. ICAM-5 overexpression in the hippocampal neurons induces filopodia formation in vitro. Since microglia are known to prune supernumerous synapses during development, we characterized the regulatory eff...

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Detalles Bibliográficos
Autores principales: Paetau, Sonja, Rolova, Taisia, Ning, Lin, Gahmberg, Carl G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5743933/
https://www.ncbi.nlm.nih.gov/pubmed/29311819
http://dx.doi.org/10.3389/fnmol.2017.00431

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5743933/
https://www.ncbi.nlm.nih.gov/pubmed/29311819
http://dx.doi.org/10.3389/fnmol.2017.00431

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