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Biomarkers of Everolimus Sensitivity in Hormone Receptor-Positive Breast Cancer
Activation of the mammalian target of rapamycin (mTOR) signaling pathway is an important mechanism of resistance to endocrine therapy in breast cancer. Everolimus, an mTOR inhibitor, has been shown to increase the efficacy of endocrine therapy and overcome resistance to endocrine therapies. Clinical...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Breast Cancer Society
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5743990/ https://www.ncbi.nlm.nih.gov/pubmed/29285035 http://dx.doi.org/10.4048/jbc.2017.20.4.321 |