Sirt3 Mediates the Inhibitory Effect of Adjudin on Astrocyte Activation and Glial Scar Formation following Ischemic Stroke

In response to stroke-induced injury, astrocytes can be activated and form a scar. Inflammation is an essential component for glial scar formation. Previous study has shown that adjudin, a potential Sirt3 activator, could attenuate lipopolysaccharide (LPS)- and stroke-induced neuroinflammation. To i...

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Detalles Bibliográficos
Autores principales: Yang, Xiao, Geng, Keyi, Zhang, Jinfan, Zhang, Yanshuang, Shao, Jiaxiang, Xia, Weiliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5744009/
https://www.ncbi.nlm.nih.gov/pubmed/29311941
http://dx.doi.org/10.3389/fphar.2017.00943

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5744009/
https://www.ncbi.nlm.nih.gov/pubmed/29311941
http://dx.doi.org/10.3389/fphar.2017.00943

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