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Chimeric Antigen Receptors T Cell Therapy in Solid Tumor: Challenges and Clinical Applications
Adoptive cellular immunotherapy (ACT) employing engineered T lymphocytes expressing chimeric antigen receptors (CARs) has demonstrated promising antitumor effects in advanced hematologic cancers, such as relapsed or refractory acute lymphoblastic leukemia, chronic lymphocytic leukemia, and non-Hodgk...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5744011/ https://www.ncbi.nlm.nih.gov/pubmed/29312333 http://dx.doi.org/10.3389/fimmu.2017.01850 |