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Chimeric Antigen Receptors T Cell Therapy in Solid Tumor: Challenges and Clinical Applications

Adoptive cellular immunotherapy (ACT) employing engineered T lymphocytes expressing chimeric antigen receptors (CARs) has demonstrated promising antitumor effects in advanced hematologic cancers, such as relapsed or refractory acute lymphoblastic leukemia, chronic lymphocytic leukemia, and non-Hodgk...

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Detalles Bibliográficos
Autores principales: Mirzaei, Hamid R., Rodriguez, Analiz, Shepphird, Jennifer, Brown, Christine E., Badie, Behnam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5744011/
https://www.ncbi.nlm.nih.gov/pubmed/29312333
http://dx.doi.org/10.3389/fimmu.2017.01850