Time resolved amplified FRET identifies protein kinase B activation state as a marker for poor prognosis in clear cell renal cell carcinoma

PURPOSE: Clear cell Renal Cell Carcinomas (ccRCC), the largest group of renal tumours, are resistant to classical therapies. The determination of the functional state of actionable biomarkers for the assessment of these adenocarcinomas is essential. The dysregulation of the oncoprotein, PKB/Akt has...

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Detalles Bibliográficos
Autores principales: Miles, James, Applebee, Christopher J., Leboucher, Pierre, Lopez-Fernandez, Sonia, Lee, Dae-Jin, Guarch, Rosa, Ward, Stephen, Parker, Peter J., López, Jose I., Larijani, Banafshé
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5744020/
https://www.ncbi.nlm.nih.gov/pubmed/29296589
http://dx.doi.org/10.1016/j.bbacli.2017.10.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5744020/
https://www.ncbi.nlm.nih.gov/pubmed/29296589
http://dx.doi.org/10.1016/j.bbacli.2017.10.002

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