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Antibacterial Activity of 1-[(2,4-Dichlorophenethyl)amino]-3-Phenoxypropan-2-ol against Antibiotic-Resistant Strains of Diverse Bacterial Pathogens, Biofilms and in Pre-clinical Infection Models

We recently described the novel anti-persister compound 1-[(2,4-dichlorophenethyl)amino]-3-phenoxypropan-2-ol (SPI009), capable of directly killing persister cells of the Gram-negative pathogen Pseudomonas aeruginosa. This compound also shows antibacterial effects against non-persister cells, sugges...

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Detalles Bibliográficos
Autores principales: Defraine, Valerie, Verstraete, Laure, Van Bambeke, Françoise, Anantharajah, Ahalieyah, Townsend, Eleanor M., Ramage, Gordon, Corbau, Romu, Marchand, Arnaud, Chaltin, Patrick, Fauvart, Maarten, Michiels, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5744096/
https://www.ncbi.nlm.nih.gov/pubmed/29312259
http://dx.doi.org/10.3389/fmicb.2017.02585