A Supercluster of Neutralizing Epitopes at the Interface of Ricin’s Enzymatic (RTA) and Binding (RTB) Subunits

As part of an effort to engineer ricin antitoxins and immunotherapies, we previously produced and characterized a collection of phage-displayed, heavy chain-only antibodies (V(H)Hs) from alpacas that had been immunized with ricin antigens. In our initial screens, we identified nine V(H)Hs directed a...

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Detalles Bibliográficos
Autores principales: Poon, Amanda Y., Vance, David J., Rong, Yinghui, Ehrbar, Dylan, Mantis, Nicholas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5744098/
https://www.ncbi.nlm.nih.gov/pubmed/29168727
http://dx.doi.org/10.3390/toxins9120378

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5744098/
https://www.ncbi.nlm.nih.gov/pubmed/29168727
http://dx.doi.org/10.3390/toxins9120378

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