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Interaction of Cholesterol with Perfringolysin O: What Have We Learned from Functional Analysis?
Cholesterol-dependent cytolysins (CDCs) constitute a family of pore-forming toxins secreted by Gram-positive bacteria. These toxins form transmembrane pores by inserting a large β-barrel into cholesterol-containing membranes. Cholesterol is absolutely required for pore-formation. For most CDCs, bind...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5744101/ https://www.ncbi.nlm.nih.gov/pubmed/29168745 http://dx.doi.org/10.3390/toxins9120381 |