Investigation of Binding Modes and Functional Surface of Scorpion Toxins ANEP to Sodium Channels 1.7

The depressant β toxin anti-neuroexcitation peptide (ANEP) from the Chinese scorpion Buthus martensii Karsch has analgesic activity by interacting with receptor site 4 of the voltage-gated sodium channels (VGSCs). Here, with molecular dynamics simulations, we examined the binding modes between ANEP...

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Detalles Bibliográficos
Autores principales: Song, Yongbo, Liu, Zeyu, Zhang, Qi, Li, Chunming, Jin, Wei, Liu, Lili, Zhang, Jianye, Zhang, Jinghai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5744107/
https://www.ncbi.nlm.nih.gov/pubmed/29186022
http://dx.doi.org/10.3390/toxins9120387

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5744107/
https://www.ncbi.nlm.nih.gov/pubmed/29186022
http://dx.doi.org/10.3390/toxins9120387

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