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Investigating β-N-Methylamino-l-alanine Misincorporation in Human Cell Cultures: A Comparative Study with Known Amino Acid Analogues

Misincorporation of β-N-methylamino-l-alanine (BMAA) into proteins has been proposed to be a mechanism of toxicity to explain the role of BMAA in neurodegenerative disease development. However, studies have shown that all detectable BMAA can be removed from proteins by SDS-PAGE purification and that...

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Detalles Bibliográficos
Autores principales: van Onselen, Rianita, Downing, Simoné, Kemp, Gabré, Downing, Tim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5744120/
https://www.ncbi.nlm.nih.gov/pubmed/29240689
http://dx.doi.org/10.3390/toxins9120400