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Mechanotransduction Mechanisms in Mitral Valve Physiology and Disease Pathogenesis

The mitral valve exists in a mechanically demanding environment, with the stress of each cardiac cycle deforming and shearing the native fibroblasts and endothelial cells. Cells and their extracellular matrix exhibit a dynamic reciprocity in the growth and formation of tissue through mechanotransduc...

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Detalles Bibliográficos
Autores principales: Pagnozzi, Leah A., Butcher, Jonathan T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5744129/
https://www.ncbi.nlm.nih.gov/pubmed/29312958
http://dx.doi.org/10.3389/fcvm.2017.00083