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Mechanotransduction Mechanisms in Mitral Valve Physiology and Disease Pathogenesis
The mitral valve exists in a mechanically demanding environment, with the stress of each cardiac cycle deforming and shearing the native fibroblasts and endothelial cells. Cells and their extracellular matrix exhibit a dynamic reciprocity in the growth and formation of tissue through mechanotransduc...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5744129/ https://www.ncbi.nlm.nih.gov/pubmed/29312958 http://dx.doi.org/10.3389/fcvm.2017.00083 |