A Bioinformatic Pipeline for Monitoring of the Mutational Stability of Viral Drug Targets with Deep-Sequencing Technology

The efficient development of antiviral drugs, including efficient antiviral small interfering RNAs (siRNAs), requires continuous monitoring of the strict correspondence between a drug and the related highly variable viral DNA/RNA target(s). Deep sequencing is able to provide an assessment of both th...

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Detalles Bibliográficos
Autores principales: Kravatsky, Yuri, Chechetkin, Vladimir, Fedoseeva, Daria, Gorbacheva, Maria, Kravatskaya, Galina, Kretova, Olga, Tchurikov, Nickolai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5744132/
https://www.ncbi.nlm.nih.gov/pubmed/29168754
http://dx.doi.org/10.3390/v9120357

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5744132/
https://www.ncbi.nlm.nih.gov/pubmed/29168754
http://dx.doi.org/10.3390/v9120357

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