Stress Granule-Inducing Eukaryotic Translation Initiation Factor 4A Inhibitors Block Influenza A Virus Replication

Eukaryotic translation initiation factor 4A (eIF4A) is a helicase that facilitates assembly of the translation preinitiation complex by unwinding structured mRNA 5′ untranslated regions. Pateamine A (PatA) and silvestrol are natural products that disrupt eIF4A function and arrest translation, thereb...

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Detalles Bibliográficos
Autores principales: Slaine, Patrick D., Kleer, Mariel, Smith, Nathan K., Khaperskyy, Denys A., McCormick, Craig
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5744162/
https://www.ncbi.nlm.nih.gov/pubmed/29258238
http://dx.doi.org/10.3390/v9120388

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5744162/
https://www.ncbi.nlm.nih.gov/pubmed/29258238
http://dx.doi.org/10.3390/v9120388

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