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Systems Pharmacology of VEGF165b in Peripheral Artery Disease
We built a whole‐body computational model to study the role of the poorly understood vascular endothelial growth factor (VEGF)(165b) splice isoform in peripheral artery disease (PAD). This model was built and validated using published and new experimental data from cells, mice, and humans, and expli...
Autores principales: | Clegg, Lindsay E., Ganta, Vijay C., Annex, Brian H., Mac Gabhann, Feilim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5744173/ https://www.ncbi.nlm.nih.gov/pubmed/29193887 http://dx.doi.org/10.1002/psp4.12261 |
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