Intravenous delivery of adeno-associated virus 9-encoded IGF-1Ea propeptide improves post-infarct cardiac remodelling

The insulin-like growth factor Ea propeptide (IGF-1Ea) is a powerful enhancer of cardiac muscle growth and regeneration, also blocking age-related atrophy and beneficial in multiple skeletal muscle diseases. The therapeutic potential of IGF-1Ea compared with mature IGF-1 derives from its local actio...

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Detalles Bibliográficos
Autores principales: Gallego-Colon, Enrique, Villalba, Maria, Tonkin, Joanne, Cruz, Francisco, Bernal, Juan Antonio, Jimenez-Borregureo, Luis J, Schneider, Michael D, Lara-Pezzi, Enrique, Rosenthal, Nadia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5744701/
https://www.ncbi.nlm.nih.gov/pubmed/29302333
http://dx.doi.org/10.1038/npjregenmed.2016.1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5744701/
https://www.ncbi.nlm.nih.gov/pubmed/29302333
http://dx.doi.org/10.1038/npjregenmed.2016.1

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