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The natural compound Jatrophone interferes with Wnt/β-catenin signaling and inhibits proliferation and EMT in human triple-negative breast cancer

Metastatic breast cancer is the leading cause of worldwide cancer-related deaths among women. Triple negative breast cancers (TNBC) are highly metastatic and are devoid of estrogen receptor (ER), progesterone receptor (PR) and human epidermal growth factor receptor 2 (HER2) amplification. TNBCs are...

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Detalles Bibliográficos
Autores principales: Fatima, Iram, El-Ayachi, Ikbale, Taotao, Ling, Lillo, M. Angeles, Krutilina, Raya, Seagroves, Tiffany N., Radaszkiewicz, Tomasz W., Hutnan, Miroslav, Bryja, Vitezslav, Krum, Susan A., Rivas, Fatima, Miranda-Carboni, Gustavo A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5744972/
https://www.ncbi.nlm.nih.gov/pubmed/29281678
http://dx.doi.org/10.1371/journal.pone.0189864