Protein-protein conjugate nanoparticles for malaria antigen delivery and enhanced immunogenicity

Chemical conjugation of polysaccharide to carrier proteins has been a successful strategy to generate potent vaccines against bacterial pathogens. We developed a similar approach for poorly immunogenic malaria protein antigens. Our lead candidates in clinical trials are the malaria transmission bloc...

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Detalles Bibliográficos
Autores principales: Scaria, Puthupparampil V., Chen, Beth, Rowe, Christopher G., Jones, David S., Barnafo, Emma, Fischer, Elizabeth R., Anderson, Charles, MacDonald, Nicholas J., Lambert, Lynn, Rausch, Kelly M., Narum, David L., Duffy, Patrick E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5744994/
https://www.ncbi.nlm.nih.gov/pubmed/29281708
http://dx.doi.org/10.1371/journal.pone.0190312

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5744994/
https://www.ncbi.nlm.nih.gov/pubmed/29281708
http://dx.doi.org/10.1371/journal.pone.0190312

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