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Protein-protein conjugate nanoparticles for malaria antigen delivery and enhanced immunogenicity
Chemical conjugation of polysaccharide to carrier proteins has been a successful strategy to generate potent vaccines against bacterial pathogens. We developed a similar approach for poorly immunogenic malaria protein antigens. Our lead candidates in clinical trials are the malaria transmission bloc...
| Autores principales: | , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5744994/ https://www.ncbi.nlm.nih.gov/pubmed/29281708 http://dx.doi.org/10.1371/journal.pone.0190312 |