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Coordinate regulation of stress signaling and epigenetic events by Acss2 and HIF-2 in cancer cells
Survival of cancer cells in the harsh tumor microenvironment, characterized by oxygen and glucose deprivation, requires rapid initiation of cytoprotective measures. Metabolites whose levels change during stress are ideal signaling cues, particularly if used in post-translational modifications of str...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5744998/ https://www.ncbi.nlm.nih.gov/pubmed/29281714 http://dx.doi.org/10.1371/journal.pone.0190241 |