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Coordinate regulation of stress signaling and epigenetic events by Acss2 and HIF-2 in cancer cells

Survival of cancer cells in the harsh tumor microenvironment, characterized by oxygen and glucose deprivation, requires rapid initiation of cytoprotective measures. Metabolites whose levels change during stress are ideal signaling cues, particularly if used in post-translational modifications of str...

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Detalles Bibliográficos
Autores principales: Chen, Rui, Xu, Min, Nagati, Jason, Garcia, Joseph A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5744998/
https://www.ncbi.nlm.nih.gov/pubmed/29281714
http://dx.doi.org/10.1371/journal.pone.0190241