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Gdf3 is required for robust Nodal signaling during germ layer formation and left-right patterning
Vertebrate embryonic patterning depends on signaling from Nodal, a TGFβ superfamily member. There are three Nodal orthologs in zebrafish; southpaw directs left-right asymmetries, while squint and cyclops function earlier to pattern mesendoderm. TGFβ member Vg1 is implicated in mesoderm formation but...
Autores principales: | Pelliccia, Jose L, Jindal, Granton A, Burdine, Rebecca D |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745080/ https://www.ncbi.nlm.nih.gov/pubmed/29140250 http://dx.doi.org/10.7554/eLife.28635 |
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