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Peptidylprolyl Isomerases as In Vivo Carriers for Drugs That Target Various Intracellular Entities
Analyses of sequences and structures of the cyclosporine A (CsA)-binding proteins (cyclophilins) and the immunosuppressive macrolide FK506-binding proteins (FKBPs) have revealed that they exhibit peculiar spatial distributions of charges, their overall hydrophobicity indexes vary within a considerab...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745455/ https://www.ncbi.nlm.nih.gov/pubmed/28961224 http://dx.doi.org/10.3390/biom7040072 |