S-Adenosylmethionine and Superoxide Dismutase 1 Synergistically Counteract Alzheimer’s Disease Features Progression in TgCRND8 Mice

Recent evidence emphasizes the role of dysregulated one-carbon metabolism in Alzheimer’s Disease (AD). Exploiting a nutritional B-vitamin deficiency paradigm, we have previously shown that PSEN1 and BACE1 activity is modulated by one-carbon metabolism, leading to increased amyloid production. We hav...

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Detalles Bibliográficos
Autores principales: Cavallaro, Rosaria A., Nicolia, Vincenzina, Fiorenza, Maria Teresa, Scarpa, Sigfrido, Fuso, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745486/
https://www.ncbi.nlm.nih.gov/pubmed/28973985
http://dx.doi.org/10.3390/antiox6040076

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745486/
https://www.ncbi.nlm.nih.gov/pubmed/28973985
http://dx.doi.org/10.3390/antiox6040076

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