The SOD Mimic, MnTE-2-PyP, Protects from Chronic Fibrosis and Inflammation in Irradiated Normal Pelvic Tissues

Pelvic radiation for cancer therapy can damage a variety of normal tissues. In this study, we demonstrate that radiation causes acute changes to pelvic fibroblasts such as the transformation to myofibroblasts and the induction of senescence, which persist months after radiation. The addition of the...

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Detalles Bibliográficos
Autores principales: Shrishrimal, Shashank, Kosmacek, Elizabeth A., Chatterjee, Arpita, Tyson, McDonald J., Oberley-Deegan, Rebecca E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745497/
https://www.ncbi.nlm.nih.gov/pubmed/29113120
http://dx.doi.org/10.3390/antiox6040087

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745497/
https://www.ncbi.nlm.nih.gov/pubmed/29113120
http://dx.doi.org/10.3390/antiox6040087

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