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Lung B cells promote early pathogen dissemination and hasten death from inhalation anthrax

Sampling of mucosal antigens regulates immune responses but may also promote dissemination of mucosal pathogens. Lung dendritic cells (LDC) capture antigens and traffic them to lung-draining lymph nodes (LDLNs) dependent on the chemokine receptor CCR7. LDCs also capture lung pathogens such as Bacill...

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Detalles Bibliográficos
Autores principales: Rayamajhi, Manira, Delgado, Christine, Condon, Tracy V., Riches, David W., Lenz, Laurel L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745579/
https://www.ncbi.nlm.nih.gov/pubmed/22472773
http://dx.doi.org/10.1038/mi.2012.21