R-100 improves pulmonary function and systemic fluid balance in sheep with combined smoke-inhalation injury and Pseudomonas aeruginosa sepsis

BACKGROUND: Septic shock is a major cause of death in intensive care units around the world . The aim of the study was to investigate whether the novel drug R-100 (a superoxide degradation catalyst and nitric oxide donor) improves pulmonary function in a sheep model of septic shock caused by Pseudom...

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Detalles Bibliográficos
Autores principales: Ito, Hiroshi, Malgerud, Erik, Asmussen, Sven, Lopez, Ernesto, Salzman, Andrew L., Enkhbaatar, Perenlei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745620/
https://www.ncbi.nlm.nih.gov/pubmed/29282084
http://dx.doi.org/10.1186/s12967-017-1366-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745620/
https://www.ncbi.nlm.nih.gov/pubmed/29282084
http://dx.doi.org/10.1186/s12967-017-1366-6

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